The pathological grades and the scores of lesions of global glomerulosclerosis, interstitial fibrosis, interstitial inflammatory infiltration, tubular atrophy and vascular injury were all increased with ageing. 全球硬化、间质纤维化、间质炎细胞浸润、肾小管萎缩、血管病变等各项积分随年龄增加升高,系膜增殖、节段硬化、球囊粘连及新月体积分在各年龄组之间无统计学差异。
And those in the naturally aged group were featured as the proliferation of kidney interstitial connective tissues and the atrophy of renal tubule epithelial cells. 自然衰老组小鼠的肾脏以肾间质结缔组织增生和肾小管上皮细胞萎缩变性为主。
The study on renal histological features with PAX2 gene mutation revealed that abnormal expression of PAX2 was related with interstitial fibrosis, tubular atrophy. 与PAX2基因突变有关的肾脏病理研究,表明PAX2异常与肾小管及其间质的病理变化有关,说明PAX2与足细胞和肾小管病理发生均有关系。
The presence of interstitial fibrosis, artery lesion and CI> 3 on biopsy contributed significantly to the prognostic value of RSR, and the presence of tubular atrophy was associated with decreased both SR and RSR. 肾活检病理参数中,RSR的下降与肾脏的慢性病理改变如肾小管的萎缩、肾间质的纤维化、CI>3以及肾小动脉的损伤均明显相关,而肾小管的萎缩还与SR的降低显著相关。
At 8w post-injection, the renal size had a decreasing trend and pathological studies showed glomerular sclerosis, renal interstitial fibrosis and tubular atrophy. 8w时肾脏出现减小的趋势,病理出现肾小球硬化、间质纤维化和肾小管萎缩。
H-E stained sections of the pancreas showed inflammatory cells infiltration, interstitial edema, and acinar cells atrophy. 模型组大鼠中,胰腺组织炎细胞浸润,间质水肿,腺泡萎缩。
The histopathological features of agingkidney: renal cortical thinning, glomerulosclerosis, renal interstitial fibrosis, tubular atrophy and arteriosclerosis. 衰老肾脏主要组织病理学表现为:肾皮质变薄、肾小球硬化、肾间质纤维化、肾小管萎缩及肾血管硬化。